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  • Well-Treated HIV Is Still Associated With Vascular Abnormalities in the Brain

    More research is needed into how the virus may affect cerebral small vessel disease, a leading cause of cognitive decline.

    28 February 2017 | Poz
  • No evidence of accelerated brain ageing in HIV positive people on effective ART

    A European study reported no evidence of accelerating brain ageing in HIV positive people in ART, based on highly sensitive brain imaging scans and cognitive testing over two year.

    19 February 2017 | HIV i-Base
  • Link found between HIV treatment, neuronal degeneration

    Certain protease inhibitors, among the most effective HIV drugs, lead to the production of the peptide beta amyloid, often associated with Alzheimer's disease, and may be the cause of cognitive problems, report researchers.

    19 December 2016 | Science Daily
  • Neurologic symptoms common in early HIV infection

    Half of people newly infected with HIV experience neurologic issues, research shows. These neurologic findings are generally not severe and usually resolve after participants started antiretroviral therapy.

    14 June 2016 | Science Daily
  • HIV-positive women with childhood trauma have double the brain trouble

    HIV-positive women who have endured a trauma such as emotional, physical or sexual abuse, or neglect earlier in their lives are more likely to have trouble remembering, paying attention or multitasking. Parts of their brains are also smaller than women who are only affected by HIV.

    26 May 2016 | The Conversation
  • Dementia in HIV -- HAND or Alzheimer's?

    Turner and colleagues at Georgetown's Memory Disorders Program argue that the usual diagnosis of dementia in HIV patients -- HIV-associated neurocognitive disorder, or HAND -- might not be the whole picture. And if some patients present with HAND, Alzheimer's or a mixture, Turner told MedPage Today, clinicians will need to broaden their differential diagnosis to get the right therapy.

    28 April 2016 | MedPage Today HIV/AIDS
  • First diagnosed case of Alzheimer's disease in HIV-positive individual reported

    Georgetown University researchers are reporting the first case of Alzheimer's disease diagnosed in an HIV-positive individual. The finding in a 71-year-old man triggers a realization about HIV survivors now reaching the age when Alzheimer's risk begins to escalate.

    15 April 2016 | Eurekalert Inf Dis
  • Last Men Standing: The Forgotten Survivors Of AIDS

    These men, then in their 20s and 30s, weren’t supposed to make it to 40. Now some are 60 years old, even 70, still alive but wounded physically, psychologically and economically. They also are suffering debilitating health problems, chronic illnesses brought on by a lifetime of living with AIDS and the toxic effects of its treatment. Many live in stark isolation, feeling abandoned and forgotten, even by the gay community they helped build here.

    11 March 2016 | San Francisco Chronicle
  • Antidepressant May Improve Cognitive Symptoms in People with HIV

    In a small, placebo-controlled clinical trial, Johns Hopkins physicians report that the antidepressant paroxetine modestly improves decision-making and reaction time, and suppresses inflammation in people with HIV-associated cognitive impairment.

    26 February 2016 | Hopkins Medicine
  • HIV/AIDS drugs interfere with brain's 'insulation,' Penn-CHOP team shows

    In a new study, researchers from the University of Pennsylvania and The Children's Hospital of Philadelphia found that commonly used antiretroviral medications disrupted the function of oligodendrocytes, crucial brain cells that manufacture myelin, the fatty material that serves to insulate neurons, helping them transmit signals in the brain fast and efficiently.

    01 December 2015 | Eurekalert Medicine & Health
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